How Ledermix Is Different
Ledermix is the only clinically proven product that has a long history of effective root canal management. It is essential for dental professionals who want to reduce the pain for their patients and be known for providing a service using reliable, superior products that are globally endorsed. We have invested heavily in ensuring the availability of an Australian made product and are fully committed to providing the leading product that provides greater benefits.
Ledermix holds a long history of providing reliable treatment
Ledermix has clinically proven results
Ledermix is endorsed by key opinion leaders and experts
Ledermix™ Paste
Ledermix™ Paste is indicated for use as an intracanal medicament in teeth undergoing
root canal treatment5,6 in the following situations:
root canal treatment5,6 in the following situations:
Acute irreversible pulpitis.
Acute apical periodontitis due to an infected root canal system. Other medicaments then need to be used as subsequent dressings (e.g. calcium hydroxide) to ensure maximum disinfection since the demeclocycline has a limited antibacterial spectrum of activity.
Inflammatory root resorption - both internal and external - as the initial dressing when the resorption is established. Other medicaments then need to be used as subsequent dressings (e.g. calcium hydroxide) to promote hard tissue repair.
To prevent the development of inflammatory resorption10,11,35 following avulsion of fully developed teeth and other injuries (e.g. intrusion of fully developed teeth) where this type of resorption is likely to occur. Its use in these situations may also reduce the amount of replacement resorption that can occur following these injuries.35
To reduce post-operative pain by reducing the periapical inflammation.7,8 If the pain is associated with an infected root canal system, then other medicaments then need to be used as subsequent dressings (e.g. calcium hydroxide) to ensure maximum disinfection since the demeclocycline has a limited antibacterial spectrum of activity.
To inhibit & reduce the number of bacteria within infected root canals. Other medicaments then need to be used as subsequent dressings (e.g. calcium hydroxide) to ensure maximum disinfection since the demeclocycline has a limited antibacterial spectrum of activity.
Ledermix™ Paste can also be used as a pulpotomy agent in the emergency management of acute irreversible pulpitis5,6 - in these cases, it should only be used as an interim pain relief measure that must be followed by more comprehensive treatment such as pulpectomy and root canal therapy.
Both zinc oxide and eugenol have well known and therapeutic effects on the pulp. Eugenol can be both anti-inflammatory and anti-microbial, depending on the concentration reaching the dentine and pulp.
Triamcinolone, released from LEDERMIX™ Cement can diffuse through the dentine to reach the pulp. In one study, 97.6% of teeth, treated with LEDERMIX™ Cement, had the reversible pulpitis resolved. 1 In addition, calcium hydroxide has beneficial effects on the healing of dental pulps and the formation of reparative dentine.
LEDERMIX™ Cement, being a hard setting material, is useful as a sedative dressing or lining under temporary or final restorations in teeth with reversible pulpitis - with or without pulp exposures. Interim crowns can be cemented using LEDERMIX™ Cement to reduce inflammation due to preparation. Additionally, LEDERMIX™ Cement can be used in the management of cracked teeth with reversible pulpitis.
For primary teeth, LEDERMIX™ Cement can be used as a root filling material following canal cleaning and preparation.
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Recommended for endodontic use
Ledermix™ has long been used for its antibacterial and anti-inflammatory properties. In recent years, Ledermix™ has gained much attention in dental traumatology as there is increasing evidence that it can inhibit inflammatory root resorption after severe lunation and avulsion injuries.
Backed by peer-reviewed studies
Ledermix™ Paste
"More than 85% of cases had complete relief of pain after a one-hour interval and more than 93% were free of pain within 24 hours of treatment."1
"More than 85% of cases had complete relief of pain after a one-hour interval and more than 93% were free of pain within 24 hours of treatment."1
1. Negem MM. Intercanal use of a corticosteroid-antibiotic compound for the management of post-treatment endodontic pain. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001; 92:435-439.
The superior choice on the market
Ledermix™ is the superior choice as other medicaments have no publications in peer-reviewed journals that support their antibacterial or anti-inflammatory efficacy, or their ability to inhibit inflammatory root resorption after severe lunation and avulsion injuries
Information For Use
In general, Ledermix™ Paste has two main therapeutic actions as a result of its two active components – one reduces inflammation whilst the other reduces the viable microbial flora within the root canal system. A further therapeutic action is by inhibition of clastic cells when managing inflammatory root resorption.
The pain associated with pulp and periapical diseases is a result of inflammation of the pulp and/or periapical tissues. Hence, in order to reduce the patient’s pain, it is essential to remove the cause of the inflammation.6 In addition, reduction of the inflammatory reaction will help to reduce pain more rapidly
The pain associated with pulp and periapical diseases is a result of inflammation of the pulp and/or periapical tissues. Hence, in order to reduce the patient’s pain, it is essential to remove the cause of the inflammation.6 In addition, reduction of the inflammatory reaction will help to reduce pain more rapidly
Application Methods
The application of preparation which has been used and well known for over 50 years, Ledermix™ Paste is what is called for. Due to the active substance, triamcinolone, Ledermix™ Paste counteracts pain symptoms promptly and quickly and leads to significant improvement.
